Developmental and medical genomics with animal models

ZENCODE-ITN Sounio workshop | October 28-31, 2018

Program

Sunday, October 28

Sepand Rastegar, Ferenc Mueller Welcome and short introduction
Monte Westerfield Keynote: Usher syndrome: insights from zebrafish
Reception

Monday, October 29

Juanma Vaquerizas Chromatin conformation in development and disease
Benjamín Hernández-Rodríguez Zebrafish 3D chromatin maps reveal conserved principles of chromatin organisation throughout vertebrates
Matthias Merkenschlager What does 3D genome organisation have to do with gene regulation?
Fiona Wardle Gene regulatory networks in zebrafish germ layer formation
Andrea Mariossi Gene regulatory analysis of endoderm development in zebrafish
Coffee break
Ferenc Mueller A cell cycle-coordinated nuclear compartment for Polymerase II transcription encompasses the earliest gene expression before global genome activation
Fabio D'Orazio A germ plasm-dependent epigenetic reprogramming provides the germ line with pluripotent features during zebrafish embryogenesis
Eivind Valen Translation scanning and initiation over early development
Sepand Rastegar Adult neurogenesis and regeneration of zebrafish telencephalon function and regulation of id1 during constitutive and regenerative neurogenesis
Swarnima Joshi Characterization of zebrafish mutant lines and deciphering the role of genes involved in motility
Lunch
Poster Session
Bernard Peers Analysis of Pax6b function in pancreatic and enteroendocrine cells reveals both tissue-specific and common regulatory networks
Claudia Dominguez Transcriptomic modifications of pancreatic cells under different metabolic status
Didier Stainier Genetic compensation and transcriptional adaptation
Coffee break
Boris Lenhard Promoter architecture and dynamics in development and differentiation
Dunja Vucenović
  • PromoterOntology – a method that gives insight into core promoter structure for a group of genes
Paul Flicek Evolution of tissue-specific mammalian gene regulation

Tuesday, October 30

Aditi Kanhere RNA dynamics in nuclear and cytosolic compartments during MZT
Sanjana Pillay Antisense non-coding RNA in zebrafish development
Albin Sandelin Using bidirectional transcription to understand fundamental biology and disease
Sanamjeet Virdi Rapid identification of ENU mutation by high-throughput sequencing
Coffee break
Carsten Daub Gene regulation underlying acute insulin response in white human adipose tissue of obese individuals is restored after weight loss by gastric bypass surgery
Abdul Kadir Mukarram Integrative annotation of genomic features in the zebrafish genome
Uwe Ohler Computational approaches to identify and interpret regulatory sequences
Piero Carninci An emerging landscape of transcriptional complexity
Matthias Hörtenhuber Ruminative science: Using publicly available sequencing data to derive novel findings
Lunch followed by social event
Jorge Ferrer DNA switches, genome kinks and type 2 diabetes
Goutham Atla Glucose dependent Genome regulation in human pancreatic isle
Hannes Lohi Canine models of human disease
Lennart Hilbert Information retrieval and three-dimensional organization in the cell nucleus
Poster Session
Dinner followed by PI/student quiz

Wednesday, October 31

Corinne Houart RNA regulation in motor development and disorders
Chris Bauer Hardware and Software development for IVD devices at the example of a mobile reader
Ana Rosa López Pérez Role of retinoic acid in endoderm regionalization
Quirze Rovira The role of Transposable Elements in Zebrafish early development
Irene Stevens Evolution of the DANIO-CODE database
Michaël Dong DANIO-CODE Data management: collection, annotation and processing
Patrick Lemaire How variable is ascidian invariant development, and why?
Sepand Rastegar, Ferenc Mueller Closing remarks
Lunch

Invited Speakers

Photo of Monte Westerfield

University of Oregon

Talk:

Keynote: Usher syndrome: insights from zebrafish

Monte Westerfield

Monte Westerfield

University of Oregon

Talk: Keynote: Usher syndrome: insights from zebrafish

Photo of Matthias Merkenschlager

MRC London Institute of Medical Sciences

Talk:

What does 3D genome organisation have to do with gene regulation?

Matthias Merkenschlager

Matthias Merkenschlager

MRC London Institute of Medical Sciences

Talk: What does 3D genome organisation have to do with gene regulation?

Photo of Eivind Valen

University of Bergen

Talk:

Translation scanning and initiation over early development

Eivind Valen

Eivind Valen

University of Bergen

Talk: Translation scanning and initiation over early development

Photo of Didier Stainier

MPI for Heart and Lung Research

Talk:

Genetic compensation and transcriptional adaptation

Didier Stainier

Didier Stainier

MPI for Heart and Lung Research

Talk: Genetic compensation and transcriptional adaptation

Photo of Paul Flicek

European Bioinformatics Institute

Talk:

Evolution of tissue-specific mammalian gene regulation

Paul Flicek

Paul Flicek

European Bioinformatics Institute

Talk: Evolution of tissue-specific mammalian gene regulation

Photo of Albin Sandelin

Copenhagen University

Talk:

Using bidirectional transcription to understand fundamental biology and disease

Albin Sandelin

Albin Sandelin

Copenhagen University

Talk: Using bidirectional transcription to understand fundamental biology and disease

Photo of Uwe Ohler

Max Delbrück Center

Talk:

Computational approaches to identify and interpret regulatory sequences

Uwe Ohler

Uwe Ohler

Max Delbrück Center

Talk: Computational approaches to identify and interpret regulatory sequences

Photo of Hannes Lohi

University of Helsinki

Talk:

Canine models of human disease

Hannes Lohi

Hannes Lohi

University of Helsinki

Talk: Canine models of human disease

Photo of Lennart Hilbert

Karlsruhe Institute of Technology

Talk:

Information retrieval and three-dimensional organization in the cell nucleus

Lennart Hilbert

Lennart Hilbert

Karlsruhe Institute of Technology

Talk: Information retrieval and three-dimensional organization in the cell nucleus

Photo of Corinne Houart

King's College London

Talk:

RNA regulation in motor development and disorders

Corinne Houart

Corinne Houart

King's College London

Talk: RNA regulation in motor development and disorders

Photo of Patrick Lemaire

CNRS

Talk:

How variable is ascidian invariant development, and why?

Patrick Lemaire

Patrick Lemaire

CNRS

Talk: How variable is ascidian invariant development, and why?

Materials

Location

The workshop will take place at the Cape Sounio.